Total Immunoglobulins (IgA, IgE, IgG, IgM)

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When measuring antibodies to identify an immune reaction, one important factor is to determine whether the immunoglobulin (antibody) mechanism is working optimally in your body. Antibody tests, such as Cyrex, measure an immunoglobulin response. Adequate immunoglobulin status will ensure that functional testing is accurate and will not result in false-negatives.

Total Immunoglobulin (IgA, IgE, IgG, and IgM) Blood Test, therefore, is a critical first step prior to ordering any additional antibody testing (such as Cyrex).

A Total Immunoglobulin (IgA, IgE, IgG, and IgM) Blood Test can be done to measure the level of each category of immunoglobulins. When the ‘Big Guns’ of your immune system are called into action, there are different branches that may respond (e.g., Total IgA for Marines, Total IgG for the Army, Total IgM for the Air Force, IgE for Navy, etc.). When we test to see if one of the Branches has been called out (e.g., an IgA response) we make the assumption the “Marines” are well-funded and well-equipped to respond.

Immunoglobulin deficiency, on the other hand, means that you are not producing adequate levels of antibodies to that branch of the “Armed Forces”. If the “Marines” have been deployed to many different locations at the same time, if they’ve been overtaxed and underfunded, their numbers may not be adequate to respond to the stress (the invader). Thus a test of the Marines (e.g., Thyroid Peroxidase Antibodies IgA on Cyrex Array 5) may come back negative due to immunodeficiency or immunosuppression. There is a problem, but the immune system cannot identify it or respond appropriately.

We recommend this panel to anyone concerned about:
the competence of their immunoglobulin response mechanism, feels it is compromised, suppressed, or just plain worn out.


*Please read the following prior to placing your lab test order*

    • All sales are final and no refunds will be afforded and you waive any rights to charge-back your purchase with your credit card processor.
    • does not participate in, take assignment, or accept any private insurance. We do not provide super bills and cannot assist with claim resolution for laboratory tests or consultations
    • Orders for this test are accepted from the United States only. The Total Immunoglobulins (IgA, IgE, IgG, IgM) from LabCorp is NOT available in the states of New York, New Jersey, Maryland and Rhode Island as per state laws.
    • Some lab providers fill out requisition forms ahead of time with client information. To avoid confusion when processing orders, if you are ordering lab kits for multiple people, please place a separate order for each person.
    • After you order a test, getting the lab draw and/or completing the test is your responsibility.
    • This test does NOT include a test interpretation consultation.  If you would like to schedule a test interpretation consultation, please contact: once you have received your test results.
    • Test interpretation consultations DO NOT include personalized recommendations. Personalized recommendations are available within our Discovery, Essentials, and Premier programs.
    • Once has received your test results, the results will be uploaded to your HIPAA compliant client portal and you will receive an email instructing you how to access them.
    • This blood draw can only be completed at a LabCorp draw center. To find the LabCorp draw center nearest you, use the following link:
    • We recommend scheduling an appointment for your blood draw in advance.
    • If you live in a remote location, you may need to travel a distance or ask your local physician or hospital to assist with phlebotomy.
    • Please contact with questions.

    Before Placing Your Order Please Read
    The Complete Terms and Conditions for LabCorp Total Immunoglobulin Test Orders at